Actively Recruiting
UMMS Sepsis Early Prediction Score (SEPSys) and RESCUE Score Combined Clinical Trial
Led by University of Maryland, Baltimore · Updated on 2026-05-05
150000
Participants Needed
8
Research Sites
147 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is designed to test two new risk scores - one designed to predict a patient's four-hour risk of developing sepsis and one designed to predict a patient's four-hour risk of deterioration (cardiac arrest, death, unplanned ICU transfer, or rapid response team call). The goal of this study is to improve provider awareness of a patient's risk of these two negative outcomes by providing them with new risk scores. The primary outcome will be the time from when the risk score becomes elevated to when vital signs such as heart rate or blood pressure are measured, suggesting an increased awareness.
CONDITIONS
Official Title
UMMS Sepsis Early Prediction Score (SEPSys) and RESCUE Score Combined Clinical Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Units are part of a member hospital of the University of Maryland Medical System (UMMS)
- Units treat inpatient patients
- Units agree to participate in the study
- Encounter is on a participating inpatient unit
- Encounter is associated with a bedded patient in the hospital
- Encounter is associated with an adult (at least 18 years of age at time of admission)
- Encounter has a SEPSys Score (for SEPSys analysis)
- Encounter has a RESCUE Score (for RESCUE analysis)
You will not qualify if you...
- Unit treats exclusively outpatients or is located in an outpatient setting
- Unit treats primarily or exclusively pediatric patients (patients under the age of 18 years old)
- Unit treats exclusively psychiatric patients
- Encounter is with OB for a normal delivery and the patient has yet to give birth (this encounter becomes eligible once birth occurs)
- Encounter is admitted with a diagnosis of sepsis
- Sepsis was already diagnosed during the encounter (SEPSys score will no longer be updated after signs or diagnosis)
- Encounter is admitted with a high RESCUE Score of 4
AI-Screening
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Trial Site Locations
Total: 8 locations
1
University of Maryland Medical Center - Midtown
Baltimore, Maryland, United States, 21201
Actively Recruiting
2
University of Maryland Medical Center
Baltimore, Maryland, United States, 21201
Not Yet Recruiting
3
University of Maryland Upper Chesapeake Medical Center
Bel Air, Maryland, United States, 21014
Not Yet Recruiting
4
University of Maryland Shore Medical Center
Easton, Maryland, United States, 21601
Not Yet Recruiting
5
University of Maryland Baltimore Washington Medical Center
Glen Burnie, Maryland, United States, 21061
Not Yet Recruiting
6
University of Maryland Charles Regional Medical Center
La Plata, Maryland, United States, 20646
Not Yet Recruiting
7
University of Maryland Capital Region Medical Center
Largo, Maryland, United States, 20774
Actively Recruiting
8
University of Maryland St. Joseph Medical Center
Towson, Maryland, United States, 21204
Not Yet Recruiting
Research Team
S
Samuel A Tisherman, MD
CONTACT
J
Jason Heavner, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
4
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