Actively Recruiting
Understanding the Neural Mechanisms Behind tDCS
Led by KU Leuven · Updated on 2024-08-30
130
Participants Needed
1
Research Sites
226 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the study is to investigate the neural mechanisms underpinning transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique in which a direct current is passed through scalp electrodes. A series of experiments will be conducted to understand and characterize the transcranial and transcutaneous mechanisms of tDCS. To investigate this research question, every participant will undergo three stimulation conditions (active, sham and control). In the control condition, an anaesthetic cream will be applied to anaesthetize the nerves in the scalp. In addition, the effectiveness of tDCS and peripheral nerve stimulation will be compared. Ultimately, the obtained knowledge can lead to the development of improved non-invasive neuromodulation therapies, which can lead to more effective treatments of a variety of neurological and psychiatric disorders.
CONDITIONS
Official Title
Understanding the Neural Mechanisms Behind tDCS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Good general health
You will not qualify if you...
- Epilepsy or family history of epilepsy
- Migraine
- Allergic to lidocaine or benzocaine
- Pregnant
- History of or currently suffering from neurological diseases
- History of or currently suffering from psychiatric diseases, depression, or anxiety
- History of brain surgery
- History of brain thrombosis
- History of cerebral hemorrhage
- History of severe head trauma
- History of meningitis
- History of long period of loss of consciousness (> 1 hour)
- Presence of metal parts in the head or upper body such as defibrillator, implanted medication pump, metal prosthesis in ear or heart
- Presence of deep brain stimulator
- History of coronary bypass or intracranial or aneurysm clips (brain arteries, aorta, etc.)
AI-Screening
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Trial Site Locations
Total: 1 location
1
KULeuven
Leuven, Vlaams-Brabant, Belgium, 3000
Actively Recruiting
Research Team
M
Myles Mc Laughlin, professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
5
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