Actively Recruiting
Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States
Led by International Maternal Pediatric Adolescent AIDS Clinical Trials Group · Updated on 2026-03-27
1150
Participants Needed
11
Research Sites
269 weeks
Total Duration
On this page
Sponsors
I
International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Lead Sponsor
U
University of Colorado, Denver
Collaborating Sponsor
AI-Summary
What this Trial Is About
IMPAACT 2046/UPLIFT (Understanding Practices of Lactation and Infant Feeding decisions Together with women with HIV) is a multi-site, mixed-methods, observational cohort study. The purpose of the study is to explore infant feeding preferences, practices, and outcomes among mothers with HIV and their families in the United States. It will employ both qualitative and quantitative research methods to address existing knowledge gaps and to understand the clinical, behavioral, and social factors influencing infant feeding decisions. As part of the study's mixed method approach, a longitudinal cohort study of mothers and their infants will be established. The study also aims to pilot a national registry of breastfeeding women living with HIV in the United States.
CONDITIONS
Official Title
Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Is of legal age or circumstance to provide independent informed consent
- Pregnant with gestational age between 28 0/7 and 37 6/7 weeks and considering or not considering breastfeeding
- Gave birth to a live born infant after February 28, 2023, is over 4 weeks postpartum, with varied breastfeeding history including no breastfeeding, breastfeeding less than four weeks and weaned, or breastfeeding for four weeks or longer
- Diagnosed with HIV prior to or during the pregnancy
- Willing to participate in interviews with a translator if preferred language is not English
- Healthcare providers who self-identify as obstetrician, midwife, nurse, infectious disease specialist, or advanced practice provider with care experience for at least five women with HIV and/or their infants in the past three years
- Ancillary healthcare professionals such as social workers, lactation support providers, patient navigators, pharmacists, or doulas with similar care experience
- Influential individuals identified by a woman with HIV as contributing to infant feeding decisions and aware of her HIV status
- Pregnant with singleton fetus at or beyond 28 0/7 weeks gestation or gave birth to a live born singleton infant up to 7 days prior to entry
- Breastfeeding postpartum women with HIV up to 7 days postpartum who have breastfed for any duration
- Pilot registry testers working at healthcare facilities providing care for breastfeeding women with HIV and their infants
You will not qualify if you...
- Presence of any condition during screening that would prevent informed consent, make participation unsafe, complicate study data interpretation, or interfere with study objectives
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 11 locations
1
University of Southern California (CRS 5048)
Los Angeles, California, United States, 90089
Not Yet Recruiting
2
David Geffen School of Medicine at UCLA (CRS 5112)
Los Angeles, California, United States, 90095
Not Yet Recruiting
3
University California, San Diego (CRS 4601)
San Diego, California, United States, 92103
Not Yet Recruiting
4
University of Colorado, Denver (CRS 5052)
Aurora, Colorado, United States, 80045
Actively Recruiting
5
University of Florida (5051)
Jacksonville, Florida, United States, 32209
Not Yet Recruiting
6
Univ of Miami Pediatric/Perinatal HIV/AIDS (5127)
Miami, Florida, United States, 33136
Not Yet Recruiting
7
5030, Emory University School of Medicine Clinical Research Site
Atlanta, Georgia, United States, 30322
Not Yet Recruiting
8
Lurie Children's Hospital of Chicago (CRS 4001)
Chicago, Illinois, United States, 60614
Actively Recruiting
9
Johns Hopkins University (CRS 5092)
Baltimore, Maryland, United States, 21287
Not Yet Recruiting
10
Jacobi Med. Ctr. Bronx NICHD CRS (5013)
The Bronx, New York, United States, 10461
Not Yet Recruiting
11
St. Jude Childrens Research Hosp, Memphis (6501)
Memphis, Tennessee, United States, 38105
Not Yet Recruiting
Research Team
L
Lisa Levy
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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