Actively Recruiting
Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE)
Led by University Hospital Southampton NHS Foundation Trust · Updated on 2026-04-30
160
Participants Needed
14
Research Sites
131 weeks
Total Duration
On this page
Sponsors
U
University Hospital Southampton NHS Foundation Trust
Lead Sponsor
N
National Institute for Health Research, United Kingdom
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is an observational trial that will look at patients undergoing endoscopic ultrasound (EUS) in patients with oesophageal cancer and to determine the proportion of cases in which EUS changes disease management in these patients.
CONDITIONS
Official Title
Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 16 or above with first diagnosis of biopsy-confirmed oesophageal cancer
- Referred for EUS examination as part of standard of care investigations
- Tumour located in the oesophagus or gastro-oesophageal junction (Siewert types I-III)
- Multi-disciplinary team decision that patient is potentially curable with radical treatment
- Prior staging with CT and PET-CT
- Eastern Cooperative Oncology Group (ECOG) performance status 0-2
- Clinical staging of T1-T4, N0-N3, M0 disease
- Adenocarcinoma or squamous cell carcinoma histopathological cell type
You will not qualify if you...
- Recurrent or residual disease
- Distant metastatic disease detected before EUS
- Previous oesophagectomy or oesophageal radiotherapy
- Unable to undergo EUS examination
- Concurrent malignancy such as a second primary tumour
- Other histopathological cell types
AI-Screening
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Trial Site Locations
Total: 14 locations
1
Cwm Taf UHB
Abercynon, United Kingdom
Actively Recruiting
2
Royal Bournemouth Hospital
Bournemouth, United Kingdom
Terminated
3
Cambridge University NHS Foundation Trust
Cambridge, United Kingdom
Actively Recruiting
4
Cardiff and Vale UHB
Cardiff, United Kingdom
Actively Recruiting
5
Velindre University NHS Trust
Cardiff, United Kingdom
Actively Recruiting
6
Glasgow Royal Infirmary
Glasgow, United Kingdom
Actively Recruiting
7
Castle Hill Hospital
Hull, United Kingdom
Actively Recruiting
8
Guy's and St Thomas' NHS Foundation Trust
London, United Kingdom
Actively Recruiting
9
Imperial College Healthcare NHS Trust
London, United Kingdom
Actively Recruiting
10
Queen's Medical Centre, Nottingham
Nottingham, United Kingdom
Actively Recruiting
11
Salford Royal Hospital
Salford, United Kingdom
Actively Recruiting
12
University Hospital Southampton
Southampton, United Kingdom
Actively Recruiting
13
Singleton Hospital, Swansea
Swansea, United Kingdom
Actively Recruiting
14
Royal Cornwall Hospital
Truro, United Kingdom
Actively Recruiting
Research Team
B
Ben Lindfield
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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