Actively Recruiting
Underwater Endoscopic Mucosal Resection Versus Metal Clips With Hot Snare Polypectomy for Resection of Big Pedunculated Colorectal Polyps
Led by Ningbo No. 1 Hospital · Updated on 2024-12-18
156
Participants Needed
1
Research Sites
149 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Endoscopic resection of pedunculated polyps mainly focuses on how to prevent bleeding, and also needs to pay attention to the convenience of resection and the integrity of resection, which means that different endoscopic resection strategies should be adopted for pedunculated polyps with different pedicle sizes. The head larger than 20mm or pedicle larger than 5mm are defined as large pedunculated polyps, which are at greater risk of bleeding. Current guidelines recommend hot removal by snare following preoperative saline injection, ligation of the pedicle with a nylon ring or metal clip, depending on the size of the polyp head and pedicle. However, the use of snares and metal clamps does not appear to reduce delayed postoperative bleeding, and the technical requirements of nylon ligation are relatively high. Recent studies have found that Underwater endoscopic mucosal resection (UEMR) is also safe and effective for the treatment of large and medium colorectal sessile polyps. Therefore, it is still necessary to further explore new safe and effective endoscopic resection strategies and techniques.
CONDITIONS
Official Title
Underwater Endoscopic Mucosal Resection Versus Metal Clips With Hot Snare Polypectomy for Resection of Big Pedunculated Colorectal Polyps
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing endoscopic resection of small and medium pedicled polyps at the First Affiliated Hospital of Ningbo University from October 2023 to August 2026
- Age between 18 and 75 years old
- Voluntary agreement to participate and signed informed consent
You will not qualify if you...
- Under 18 years of age
- Unwilling or unable to provide informed consent
- Treatment or radiotherapy for malignant diseases
- Severe chronic heart or lung diseases
- Coronary or cerebrovascular events requiring hospitalization within the last 3 months
- Malignant polyps infiltrating the pedicle
- Severe abdominal symptoms such as pain, distension, or nausea
- Inadequate intestinal preparation
- Lifelong anticoagulant therapy or severe bleeding disorders
- Recent use of anticoagulant or antiplatelet drugs within 1 week
- Pregnant or lactating
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
the First Affiliated Hospital of Ningbo University
Ningbo, Zhejiang, China, 315000
Actively Recruiting
Research Team
L
Lei Xu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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