Actively Recruiting

Phase Not Applicable
Age: 40Years - 80Years
All Genders
NCT05481697

Unintentional Weight Loss and Cancer: A Prospective Trial of Patient-centered Weight Tracking Combin

Led by Case Comprehensive Cancer Center · Updated on 2026-02-19

1000

Participants Needed

1

Research Sites

191 weeks

Total Duration

On this page

Sponsors

C

Case Comprehensive Cancer Center

Lead Sponsor

U

University Hospitals Seidman Cancer Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

Unintentional weight loss (UWL) is commonly associated with a wide variety of diseases and there is still no valid diagnostic pathway for evaluating UWL. When detecting UWL coupled with GRAIL Galleri testing, (an investigational pan-cancer early detection test), it is thought that there is a greater positive predictive value in detecting malignancies. This study aims to test the potential synergistic effects of UWL detection and GRAIL usage to detect malignancy at an even earlier rate. UWL will be measured using weekly weight tracking.

CONDITIONS

Official Title

Unintentional Weight Loss and Cancer: A Prospective Trial of Patient-centered Weight Tracking Combin

Who Can Participate

Age: 40Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 40 and 80 years
  • Access to a device compatible with the Fitbit Aria Air smart scale
  • Willingness to follow all study procedures and be available for the entire study duration
  • Mentally competent, able to understand and willing to sign informed consent
  • Able to speak English to understand the trial rationale and procedures
Not Eligible

You will not qualify if you...

  • Current cancer diagnosis, undergoing cancer treatment, or completed treatment within the past 3 years
  • Actively trying to lose weight using medications or bariatric surgery
  • Pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center

Cleveland, Ohio, United States, 44106

Actively Recruiting

Loading map...

Research Team

J

Jordan M Winter, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SCREENING

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here