Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID06466005

UnityPhilly Response App for Overdose Reversal: Assessing Citywide Effectiveness and Sustainability

Led by Drexel University · Updated on 2026-05-12

450

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

Sponsors

D

Drexel University

Lead Sponsor

U

University of Michigan

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating if the UnityPhilly overdose prevention app can encourage people to respond and prevent opioid overdoses in Philadelphia. This behavioral clinical trial focuses on how different groups of individuals use the app, along with training and naloxone provision, to react to overdoses and reduce opioid-related harm. The study will enroll participants from various backgrounds, such as active opioid users, people in recovery, caregivers, and concerned community members. Participants will receive the UnityPhilly app and training on its use and how to respond to opioid overdoses using naloxone. All 450 enrolled participants will use the app over a 12-month period, and the study will track their responses and experiences. Additionally, 3,000 community volunteers will be engaged over two years to assess the app's sustainability and community reach. During the study, participants will complete surveys and interviews about their experiences with the app and overdose response. Researchers will collect data on overdose alerts, responses, and reversals, examining these outcomes over time. The study will also evaluate the app's adoption and effectiveness across different user groups and neighborhoods, with a total follow-up duration extending up to two years.

CONDITIONS

Brief Title

UnityPhilly Response App for Overdose Reversal

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Own a smartphone with a data package
  • Live or work in one of three identified Philadelphia neighborhoods
  • Be aged 18 years or older
Not Eligible

You will not qualify if you...

  • Persons under 18 years of age

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote)

Implementation

Duration - Up to 9 months enrollment period

Participants learn how to use the UnityPhilly app and receive training on overdose prevention and naloxone use.

1 training visit

Long-term Monitoring

Duration - 24 months

Participants use the UnityPhilly app and are monitored over a 2-year period to assess the effectiveness and sustainability of the app in responding to opioid overdoses.

Baseline assessment and periodic follow-ups over 24 months

Trial Site Locations

Total: 1 location

1

Drexel University

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

S

Stephen Lankenau, PhD

K

Kushal Naik, MPH

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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