Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06466005

UnityPhilly Response App for Overdose Reversal

Led by Drexel University · Updated on 2026-05-12

450

Participants Needed

1

Research Sites

145 weeks

Total Duration

On this page

Sponsors

D

Drexel University

Lead Sponsor

U

University of Michigan

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to discover if an overdose prevention app (UnityPhilly) can encourage citizen responders to respond and prevent opioid overdoses using the UnityPhilly app. The main hypotheses to answer are: Hypothesis 1: UnityPhilly signal rates relative to EMS calls will increase over time. The primary outcome will be assessed as the total number of overdoses signaled by participants relative to all overdose-related EMS calls, per year. Hypothesis 2: The number of cases where a nearby UnityPhilly participant successfully reverses an overdose with naloxone will increase over time. The primary outcome will be assessed as the number of successful reversals relative to the total number of responder arrivals, per year. Participants will be supplied with the UnityPhilly app, training on how to use the app and respond to an opioid overdose using naloxone, and respond to follow up surveys about their experiences.

CONDITIONS

Official Title

UnityPhilly Response App for Overdose Reversal

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Own a smartphone with a data package
  • Live or work in one of three identified Philadelphia neighborhoods
  • Be aged 18 years or older
Not Eligible

You will not qualify if you...

  • Persons younger than 18 years old

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Drexel University

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

S

Stephen Lankenau, PhD

CONTACT

K

Kushal Naik, MPH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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UnityPhilly Response App for Overdose Reversal | DecenTrialz