Actively Recruiting
Universal CAR-T Cell Therapy for NHL
Led by Bioray Laboratories · Updated on 2025-11-25
6
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
Sponsors
B
Bioray Laboratories
Lead Sponsor
S
Shanghai Tongji Hospital, Tongji University School of Medicine
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a single-center, single-arm, open-label clinical study, and the sample size is set to 3-6 subjects.
CONDITIONS
Official Title
Universal CAR-T Cell Therapy for NHL
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willing to participate and sign informed consent
- Age 18 years or older
- Estimated survival time of at least 3 months
- At least one measurable lesion
- CD19 expression positive
- ECOG performance score of 0-1
- Hematology, coagulation, and biochemistry results meet study requirements
- Left ventricular ejection fraction (LVEF) of 55% or higher
- No severe lung disorders
You will not qualify if you...
- Pregnant or breastfeeding women
- Previous allogeneic cell therapies, including stem cell transplant
- Prior anti-CD19 targeted therapy
- Previous CAR-T cell or genetically modified T cell treatments
- History of Richter's transformation of chronic lymphocytic leukemia
- Uncontrolled infections requiring systemic treatment
- Positive for hepatitis B, hepatitis C, HIV, or syphilis with active infection
- Severe mental health disorders or CNS diseases
- Active autoimmune disorders needing immunotherapy within past 2 years
- Primary immunodeficiency
- History of other cancers
- Severe cardiovascular diseases
- Any condition increasing risk or interfering with study as judged by investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghi Tongji Hospital (Tongji Hospital of Tongji University)
Shanghai, China, 620000
Actively Recruiting
Research Team
P
Ping Li, phD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here