Actively Recruiting
University of Michigan COPD Identification Through Lung Cancer Screening Cohort Study - MAP2
Led by University of Michigan · Updated on 2026-03-25
200
Participants Needed
1
Research Sites
72 weeks
Total Duration
On this page
Sponsors
U
University of Michigan
Lead Sponsor
C
COPD Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to obtain new knowledge regarding screening for COPD. This study will use a participant's cancer screening CT scans performed as part of routine health care among current and former smokers at risk for COPD to identify participants who have had a spirometry or will have a spirometry test as part of the study to verify COPD status.
CONDITIONS
Official Title
University of Michigan COPD Identification Through Lung Cancer Screening Cohort Study - MAP2
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Eligible for lung cancer screening by USPSTF 2021 criteria including age 50-80 years and currently or formerly smoking with at least 20 pack-years of smoking history at the time of consent.
- Willingness to participate in an observational clinical trial and to be contacted about future ancillary studies that could include interventional clinical trials.
- Ability to tolerate study procedures.
- Ability to provide informed consent.
- Clinical Lung Cancer Screening CT performed at the University of Michigan within the last year.
- Meets one of the three following criteria:
- Prior Diagnosis of COPD in the EMR
- Prior pulmonary function meeting criteria for COPD (FEV1/FVC �3C= 0.70) or
- LAA>1% on lung cancer screening CT scan
You will not qualify if you...
- Presence of a respiratory condition other than COPD or asthma, or a comorbid condition that may be the main cause of respiratory symptoms.
- Severe asthma defined as current GINA Step 4 or higher therapy or 3 or more unscheduled healthcare visits for asthma in the past 12 months or one asthma hospitalization in the past 12 months.
- Concurrent participation in a blinded therapeutic trial.
- Active pregnancy; birth control documentation required for pre-menopausal women.
- Cognitive dysfunction preventing completion of study procedures.
- BMI over 35 kg/m2 at baseline.
- Current illicit substance abuse, including cannabis smoking.
- Any illness expected to cause mortality within 3 years.
- Implanted metallic devices or prosthesis above the waist that could affect CT scan quality.
- History of thoracic radiation or thoracic surgery with lung tissue resection.
- Acute COPD exacerbation within last 30 days unless rescreened after 30 days.
- Current use of acute antibiotics or steroids unless rescreened 30 days after stopping; does not apply to chronic low-dose prednisone or prophylactic antibiotics.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Michigan
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here