Actively Recruiting
Upfront Surgical Resection for Osteosarcoma
Led by Montefiore Medical Center · Updated on 2026-03-16
10
Participants Needed
1
Research Sites
244 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this pilot study is to learn about patients with newly diagnosed osteosarcoma of an extremity, and whether surgically removing the tumor prior to the administration of any chemotherapy will improve functional outcomes. In order to learn about the patient's experience, the study team will administer questionnaires to the patient and surgeon at various timepoints to assess recovery and the function of the extremity.
CONDITIONS
Official Title
Upfront Surgical Resection for Osteosarcoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Newly diagnosed, untreated, localized high-grade osteosarcoma of an extremity verified by histopathology
- Plans to have upfront surgical removal of the tumor followed by systemic chemotherapy
- Performance status of 0, 1, or 2 according to ECOG (Karnofsky used if >16 years, Lansky if ≤16 years)
You will not qualify if you...
- Presence of metastatic disease at diagnosis
- Starting systemic therapy before enrollment
- Previous history of cancer
- Previous radiation therapy
- Active life-threatening infection
- Pregnancy (must have a negative pregnancy test if female of childbearing potential)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Montefiore Medical Center
The Bronx, New York, United States, 10467
Actively Recruiting
Research Team
R
Rebecca Zylber, NP
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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