Actively Recruiting
Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis
Led by University of Texas, El Paso · Updated on 2024-12-16
60
Participants Needed
1
Research Sites
100 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of the study is to explore the effects of arm exercise (UE, arm ergometer) vs. leg exercise (LE, cycling ergometer) on exercise-induced hypoalgesia (EIH), central pain mechanisms and knee pain in people with knee osteoarthritis (OA). Furthermore, we will explore relations of socioeconomic status, racial discrimination, acculturative stress, and autonomic function to exercise effects on EIH, central pain mechanisms, and knee pain. This will be a pilot randomized cross-over study where all participants undergo Day 1 (baseline assessments), Day 2 (UE or LE), and Day 3 (UE or LE).
CONDITIONS
Official Title
Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 45 years or older
- Diagnosis of knee osteoarthritis using clinical criteria
- Activity-related knee pain
- Morning joint stiffness lasting 30 minutes or less, or no stiffness
- Knee pain rated at least 4 out of 10
- Knee pain is the main complaint if multiple pains exist
- Ability to understand English
You will not qualify if you...
- Peripheral neuropathy or loss of sensation at wrist, knee, or forearm
- Use of electrically active medical devices (e.g., pacemaker)
- Chronic opioid use
- Pregnancy
- Serious uncontrolled diseases including cardiovascular, nervous system, pulmonary, renal, hepatic, metabolic, hormonal, endocrine, gastrointestinal, or epilepsy
- Rheumatoid arthritis, ankylosing spondylitis, or neurological disorders preventing study procedures
- Cognitive impairment
- History of knee replacement surgery
- Inability to exercise due to severe pain or symptoms
- Knee pain interventions in the past 3 months
- Pain-free controls must not have had any pain episodes from musculoskeletal injury or other causes in the last 3 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Texas at El Paso
El Paso, Texas, United States, 79968
Actively Recruiting
Research Team
K
Kosaku Aoyagi, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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