Actively Recruiting
Upper Punctal Plug Occlusion in Previous Lower Punctal Occlusion.
Led by Universidad Autonoma de Nuevo Leon · Updated on 2026-05-06
36
Participants Needed
1
Research Sites
37 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study evaluates the therapeutic effect of upper punctal plug occlusion in patients with dry eye disease with previous lower punctal occlusion.
CONDITIONS
Official Title
Upper Punctal Plug Occlusion in Previous Lower Punctal Occlusion.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients of both sexes
- One or both eyes may be included
- Inferior lacrimal punctum occluded (with a punctal plug or cauterization), clinically sealed under slit-lamp examination
- Functional superior lacrimal punctum
- Aqueous-deficient dry eye (such as Sj�f6gren's disease, graft-versus-host disease, or primary dry eye disease)
- Age >18 years
- OSDI score >13 and one of the following signs: Tear film markers (Fluorescein tear break up-time <5, First non-invasive tear breakup time <10, Schirmer test without anesthesia <10 mm, Schirmer test with anesthesia <10 mm), Ocular surface markers (corneal staining >5 spots or conjunctival staining >9 spots)
You will not qualify if you...
- Active ocular surface infection
- Patients who are unwilling to participate or to provide written informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ophthalmology Department
Monterrey, Nuevo León, Mexico, 64460
Actively Recruiting
Research Team
K
Karim Mohamed-Noriega, Dr. med.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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