Actively Recruiting

Phase Not Applicable
Age: 45Years +
All Genders
NCT06799832

Urethral PeRfusion Index-Guided Hemodynamic ManagemenT in Patients Having Major Abdominal Surgery: the UPRIGHT Randomized Feasibility Trial

Led by Universitätsklinikum Hamburg-Eppendorf · Updated on 2025-02-21

116

Participants Needed

2

Research Sites

27 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

We will perform this single-center pilot trial to determine if the intraoperative urethral perfusion index is higher in patients assigned to maintaining postinduction baseline urethral perfusion index than in patients assigned to routine care (with blinded urethral perfusion index monitoring). As pre-planned substudies, we will also assess the agreement between a) urethral perfusion index-derived pulse rate and heart rate measured with an electrocardiogram and b) between the urethral perfusion index and the peripheral perfusion index.

CONDITIONS

Official Title

Urethral PeRfusion Index-Guided Hemodynamic ManagemenT in Patients Having Major Abdominal Surgery: the UPRIGHT Randomized Feasibility Trial

Who Can Participate

Age: 45Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 45 years or older
  • Scheduled for elective major abdominal surgery involving visceral organs with an expected duration of at least 120 minutes
  • Indication for an arterial catheter
  • Indication for a urinary catheter
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Planned nephrectomy, liver transplantation, or kidney transplantation surgery
  • Previous surgery on the urethra or bladder
  • No clinical indication for continuous blood pressure monitoring with an intraarterial catheter

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

University Medical Center Hamburg-Eppendorf

Hamburg, Germany

Not Yet Recruiting

2

University Medical Center Hamburg-Eppendorf

Hamburg, Germany

Actively Recruiting

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Research Team

B

Bernd Saugel, MD

CONTACT

M

Moritz Flick, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Urethral PeRfusion Index-Guided Hemodynamic ManagemenT in Patients Having Major Abdominal Surgery: the UPRIGHT Randomized Feasibility Trial | DecenTrialz