Evaluating Urethral Resistive Index as a New Non-Invasive Test for Diagnosing Urethral Obstruction in Men Aged 18 to 80

What this Trial Is About

Researchers are evaluating a new, non-invasive diagnostic method called the Urethral Resistive Index URI to detect urethral stricture in men. This observational study aims to see if URI can accurately diagnose urethral obstruction without needing invasive procedures like surgery or pressure-flow studies. The study involves men aged 18 to 80 years, including those with suspected urethral stricture and healthy volunteers, to compare results and validate the new parameter. Participants will undergo two uroflowmetry tests a standard natural voiding test followed by a forced voiding session using the Valsalva maneuver. The URI is calculated by comparing the maximum flow rates from these two sessions. The study includes 30 men with confirmed urethral stricture scheduled for surgery and 30 healthy male volunteers without urinary symptoms. Data collection occurs at a specialized urology clinic. During the study, researchers will gather clinical and uroflowmetric data, including the URI measured at baseline during the uroflowmetry sessions. They will analyze the diagnostic accuracy of URI using statistical methods to find the best cut-off value for detecting urethral stricture. The study also assesses symptom scores and monitors participants for any discomfort during testing. The total participation period varies but focuses on these two uroflowmetry assessments.

Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral Obstruction