Actively Recruiting

Age: 50Years - 70Years
MALE
Healthy Volunteers
NCT06992986

Urinary Microbiome Differences in Bladder Cancer, Benign Urinary Diseases and Healthy Counterparts in Adult Male Population

Led by Regina Elena Cancer Institute · Updated on 2025-05-28

50

Participants Needed

1

Research Sites

73 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study aims to investigate alterations in the bladder microbiome in adult men with bladder cancer, healthy men, and men with benign urinary disease

CONDITIONS

Official Title

Urinary Microbiome Differences in Bladder Cancer, Benign Urinary Diseases and Healthy Counterparts in Adult Male Population

Who Can Participate

Age: 50Years - 70Years
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men aged 50 to 70 years
  • Diagnosis of bladder cancer with histological confirmation of urothelial carcinoma
  • Negative urine culture
  • Patients undergoing radical cystectomy
  • Healthy male controls within the specified age range
  • Men with benign urinary diseases such as renal cysts, benign prostatic obstruction, or ureteral obstruction undergoing surgery
Not Eligible

You will not qualify if you...

  • Presence of other cancers
  • History of previous BCG therapy
  • Use of indwelling catheter
  • Active antibiotic treatment within two months prior to participation
  • History of sexually transmitted diseases
  • Presence of chronic intestinal inflammation
  • Prior neoadjuvant therapy
  • Diabetes
  • Chronic kidney disease
  • Cardiac disease
  • Liver disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

"Regina Elena" National Cancer Institute

Rome, Italy, 00144

Actively Recruiting

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Research Team

G

Giuseppe Simone, Doctor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Urinary Microbiome Differences in Bladder Cancer, Benign Urinary Diseases and Healthy Counterparts in Adult Male Population | DecenTrialz