Actively Recruiting
Urine HPV Testing for Cervical Cancer Screening Among Women Living With HIV in South Africa
Led by UNC Lineberger Comprehensive Cancer Center · Updated on 2025-06-29
300
Participants Needed
1
Research Sites
168 weeks
Total Duration
On this page
Sponsors
U
UNC Lineberger Comprehensive Cancer Center
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study explores the usefulness of urine samples for cervical cancer screening in human immunodeficiency virus (HIV)-infected women. Cervical cancer occurs when women are infected with the human papillomavirus (HPV), which can cause changes in the cells that lead to cervical precancer and, eventually, cervical cancer if untreated. However, urine HPV testing has not been well validated low- and middle-income country settings, with no data available to guide its use in HIV-infected women.
CONDITIONS
Official Title
Urine HPV Testing for Cervical Cancer Screening Among Women Living With HIV in South Africa
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed HIV-1 infection
- Age 25 years and older
- Willing and able to provide written informed consent
You will not qualify if you...
- Pregnant or planning to become pregnant within 90 days of enrollment
- Screened for cervical cancer within the preceding year
- Have an active sexually transmitted infection (may participate once treated)
- Surgically absent cervix
- History of cervical cancer
- Previously vaccinated against HPV
AI-Screening
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Trial Site Locations
Total: 1 location
1
Clinical HIV Research Unit Temba Lethu Wing Helen Joseph Hospital
Westdene, Johannesburg, South Africa, 2092
Actively Recruiting
Research Team
C
Cheryl Hendrickson
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
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