Actively Recruiting

Age: 20Years +
All Genders
NCT04712305

Urine Omics Predicting IO Therapy Responses in mRCC Patients

Led by National Taiwan University Hospital · Updated on 2022-01-20

400

Participants Needed

1

Research Sites

364 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study aims to identify urinary metabolite and protein markers that can predict anti-tumor efficacy and adverse events in subjects receiving IO-based therapies for metastatic renal cell carcinoma.

CONDITIONS

Official Title

Urine Omics Predicting IO Therapy Responses in mRCC Patients

Who Can Participate

Age: 20Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age > 20 years
  • Diagnosed with advanced or metastatic renal cell carcinoma
  • About to receive immuno-oncology (IO) based therapy
  • ECOG performance status 0, 1, 2, or 3
  • Life expectancy greater than 3 months
  • Estimated glomerular filtration rate (eGFR) greater than 15 ml/min/1.73 m2
  • Willing to sign the informed consent form
Not Eligible

You will not qualify if you...

  • Not willing to sign the informed consent form
  • Active infection or urinary tract infection with urinary white blood cells > 5/HPF
  • Other malignancies requiring active treatment (except those not needing treatment)
  • Taking immune-modulating agents like corticosteroids or immune-suppressants
  • Previous treatment with immuno-oncology (IO) therapy
  • Received systemic anti-cancer therapies within 4 weeks before screening (except targeted therapy)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

National Taiwan University Hospital

Taipei, Taiwan, 100

Actively Recruiting

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Research Team

Y

Yeong Shiau Pu, MD PhD

CONTACT

C

Chung Hsin Chen, MD PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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