Actively Recruiting
Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery
Led by Mayo Clinic · Updated on 2026-04-03
20
Participants Needed
1
Research Sites
142 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this research is to see if the use of tamsulosin can decrease both the incidence and duration of urinary retention, as well as hospital length of stay following spine surgery.
CONDITIONS
Official Title
Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled for cervical laminectomy
- Scheduled for cervical posterior fusion
- Scheduled for cervical anterior/posterior fusion
- Scheduled for lumbar laminectomy
- Scheduled for lumbar posterolateral fusion
- Scheduled for lumbar interbody fusion
You will not qualify if you...
- Scheduled for cervical anterior discectomy and fusion
- Scheduled for cervical anterior corpectomy
- Scheduled for cervical posterior discectomy
- Scheduled for cervical foraminotomy
- Scheduled for lumbar discectomy (METRx or open)
- Scheduled for lumbar foraminotomy
- Scheduled for lumbar anterior fusion
- Has myelopathy with bladder dysfunction
- Currently taking alpha-antagonist drugs such as alfuzosin, doxazosin, prazosin, terazosin, tamsulosin, or phenoxybenzamine
- History of allergy or sensitivity to tamsulosin or other alpha-antagonists
- History of prostatectomy or urologic surgery involving bladder or urethra
- Has severe liver disease or end-stage renal disease
- Taking strong inhibitors of CYP3A4 like ketoconazole, itraconazole, clarithromycin, ritonavir, indinavir/ritonavir, lopinavir/ritonavir, or conivaptan
- Has mental disability or is a prisoner
- Pregnant (for anesthesia purposes)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
N
Neurologic Surgery Research Team
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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