Actively Recruiting

All Genders
ID05820672

A US Multi-center, Prospective, Non-interventional, Long Term, Effectiveness and Safety Study of Patients Treated With SKYTROFA (Lonapegsomatropin)

Led by Ascendis Pharma Endocrinology Division A/S · Updated on 2026-04-21

900

Participants Needed

27

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to gather long-term evidence on the safety and effectiveness of SKYTROFA (lonapegsomatropin) in patients with growth hormone deficiency who are receiving routine clinical care. The study focuses on understanding how patients respond to this treatment over time without altering their usual medical management. It is a non-interventional observational study conducted across multiple centers in the USA. Patients will continue their regular treatment with SKYTROFA as managed by their healthcare providers, with no additional visits, examinations, or tests required beyond standard clinical care. The study will collect data from clinical outcome assessments (COAs) to evaluate treatment results and safety over a period of five years. No experimental interventions or placebos are involved. Participants will be monitored through their routine clinical visits, with researchers reviewing their health status and treatment effectiveness using standard assessments. The primary outcomes include measuring safety and treatment effectiveness over five years, along with evaluating clinical outcomes through COAs. This approach allows for natural observation of patient experiences without extra procedures or disruptions to their care.

CONDITIONS

Brief Title

A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who are on treatment with SKYTROFA (lonapegsomatropin)
  • Patients being clinically managed in USA
  • Patients with an appropriate written informed consent or assent as applicable for their age
Not Eligible

You will not qualify if you...

  • Patients participating in any interventional clinical study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Long-term Monitoring

Duration - Up to 5 years

Participants who undergo routine care are observed to assess safety and effectiveness of SKYTROFA treatment over time.

Visits and assessments occur as part of routine clinical practice with no additional required visits

Trial Site Locations

Total: 27 locations

1

Ascendis Investigational Site

Phoenix, Arizona, United States, 85054

Actively Recruiting

2

Ascendis Investigational Site

Orange, California, United States, 92868

Actively Recruiting

3

Ascendis Investigational Site

Sacramento, California, United States, 95821

Actively Recruiting

4

Ascendis Investigational Site

San Francisco, California, United States, 94143

Actively Recruiting

5

Ascendis Pharma Investigational Site

Centennial, Colorado, United States, 80112

Actively Recruiting

6

Ascendis Investigational Site

Washington D.C., District of Columbia, United States, 20010

Actively Recruiting

7

Ascendis Investigational Site

Orlando, Florida, United States, 32806

Actively Recruiting

8

Ascendis Investigational Site

Orlando, Florida, United States, 32827

Actively Recruiting

9

Ascendis Investigational Site

Tampa, Florida, United States, 33612

Actively Recruiting

10

Ascendis Investigational Site

Sandy Springs, Georgia, United States, 30350

Actively Recruiting

11

Ascendis Investigational Site

Boise, Idaho, United States, 83712

Actively Recruiting

12

Ascendis Investigational Site

Indianapolis, Indiana, United States, 46202

Actively Recruiting

13

Ascendis Investigational Site

Iowa City, Iowa, United States, 52242

Actively Recruiting

14

Ascendis Investigational Site

Louisville, Kentucky, United States, 40202

Actively Recruiting

15

Ascendis Investigational Site

Minneapolis, Minnesota, United States, 55455

Actively Recruiting

16

Ascendis Investigational Site

Las Vegas, Nevada, United States, 89113

Actively Recruiting

17

Ascendis Investigational Site

Lebanon, New Hampshire, United States, 03756

Actively Recruiting

18

Ascendis Investigational Site

Manchester, New Hampshire, United States, 03104

Actively Recruiting

19

Ascendis Investigational Site

Morristown, New Jersey, United States, 07960

Actively Recruiting

20

Ascendis Investigational Site

New Hyde Park, New York, United States, 11042

Actively Recruiting

21

Ascendis Investigational Site

Cincinnati, Ohio, United States, 45229

Actively Recruiting

22

Ascendis Investigational Site

Portland, Oregon, United States, 97239

Actively Recruiting

23

Ascendis Investigational Site

Columbia, South Carolina, United States, 29203

Actively Recruiting

24

Ascendis Investigational Site

Dallas, Texas, United States, 75390

Actively Recruiting

25

Ascendis Investigational Site

El Paso, Texas, United States, 79907

Actively Recruiting

26

Ascendis Investigational Site

Norfolk, Virginia, United States, 23507

Actively Recruiting

27

Ascendis Investigational Site

Seattle, Washington, United States, 98105

Actively Recruiting

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Research Team

D

Deborah Bowlby

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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