Observational Study of Parkinsons Disease Patients with Movement Symptoms Despite Standard Oral Treatments

What this Trial Is About

This observational study focuses on people with Parkinsons disease who continue to have movement symptoms despite taking standard Parkinsons medications. Researchers aim to better understand how the disease progresses over time, the challenges faced by patients and their care partners, and how current treatments work in real life. The study is designed to fill gaps in knowledge by following patients longer and collecting comprehensive information. Participants will continue their usual treatments as determined by their doctors, without any investigational drugs or changes to their care plans. Data will be collected from patients and care partners through questionnaires, medical records, digital movement tracking devices, blood samples, and skin biopsies. The study includes a single group of patients with motor complications and their care partners. Participants will be followed for up to five years, with data collected on demographics, medical history, medications, movement and non-movement symptoms, genetics, and the burden of care. Researchers will use rating scales, diaries, and logs to assess symptoms and quality of life. The main outcomes include summaries of motor and non-motor symptoms, treatments received, and psychological and economic impacts on care partners.

A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications