Actively Recruiting
Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions
Led by Weill Medical College of Cornell University · Updated on 2025-08-03
100
Participants Needed
1
Research Sites
463 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine. One hundred subjects undergoing clinically-indicated, standard-of-care cardiac electrophysiology study (EPS) procedure for PVCs will receive adenosine and/or verapamil to learn if their arrhythmias are inducible similarly to sustained ventricular tachycardia.
CONDITIONS
Official Title
Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of premature ventricular contractions (PVCs)
- Scheduled for an electrophysiology study with the intent to perform cardiac ablation for PVCs
- Male or female aged between 18 and 70 years
- Able to provide informed consent
You will not qualify if you...
- Presence of any structural heart disease
- Coronary artery disease with 70% or more stenosis
- Current use of anti-arrhythmic drugs
- Pregnancy
- Asthma if adenosine will be administered
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Weill Cornell Medicine
New York, New York, United States, 10065
Actively Recruiting
Research Team
J
James E Ip, M.D
CONTACT
D
Dolores T Reynolds, BSN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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