Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06275555

Use of Bivalirudin for Anticoagulation in Patients With Extracorporeal Membrane Oxygenation

Led by Xiaotong Hou · Updated on 2026-04-06

154

Participants Needed

1

Research Sites

143 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study was to evaluate the efficacy and safety of bivalirudin in anticoagulation therapy in patients with extracorporeal membrane oxygenation (ECMO) compared with unfractionated heparin.

CONDITIONS

Official Title

Use of Bivalirudin for Anticoagulation in Patients With Extracorporeal Membrane Oxygenation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Receiving VA-ECMO or VV-ECMO
  • Systemic anticoagulation needed with APTT maintained at 40-60 seconds
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • History of allergy to heparin or bivalirudin
  • Previous diagnosis of heparin-induced thrombocytopenia
  • ECMO assistance for more than 48 hours before randomization
  • Pregnant female
  • Prior participation in this study
  • Other factors deemed unsuitable by researchers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beijing Anzhen Hospital

Beijing, Beijing Municipality, China, 100029

Actively Recruiting

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Research Team

X

Xiaotong Hou, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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