Actively Recruiting
Use of CEST (Chemical Exchange Saturation Transfer) Imaging in PET/MRI
Led by Centre Paul Strauss · Updated on 2026-02-02
800
Participants Needed
1
Research Sites
730 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Standard Magnetic Resonance Imaging (MRI) is based on the excitation of hydrogen nuclei that are presents in water molecules, which abundance in human body allows for obtention of superior contrast. However, assessing the presence of other molecules than water in tissues is also of great clinical interest to probe metabolites related to physiological body function and pathological conditions. Chemical exchange saturation transfer (CEST) allow to overcome some limitations of proton magnetic resonance spectroscopy (1H-MRS) by exploiting chemical properties of the targeted molecule through a continuous process of re-saturation and exchange, and thus detecting it with increased sensitivity, from two orders of magnitude. Moreover, CEST technique is based on imaging sequences and can therefore benefit from well-known fast acquisition strategies, as well as improved spatial resolution.
CONDITIONS
Official Title
Use of CEST (Chemical Exchange Saturation Transfer) Imaging in PET/MRI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients admitted for a PET/MRI exam for preoperative evaluation of a cerebral expansion lesion
- Patients undergoing evaluation of glioma recurrences
- Patients undergoing evaluation of brain metastases
- Patients undergoing evaluation of recurrence of metastases
You will not qualify if you...
- Contraindication to MRI
- Minors or patients under guardianship or supervision
- Patients deprived of liberty
- Patients under judicial protection
- Patients unable to give consent
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
France Institut de cancérologie Strasbourg Europe
Strasbourg, France
Actively Recruiting
Research Team
M
Manon VOEGELIN
CONTACT
C
Claire VIT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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