Actively Recruiting
Use of Cryopressotherapy in Patiens Undergoing Total Knee Replacement to Improve Clinical Outcome
Led by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · Updated on 2026-03-06
78
Participants Needed
1
Research Sites
122 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the effectiveness of cryopressotherapy in patients undergoing total knee arthroplasty by assessing clinical improvement using the KOOS at 14 days after surgery. Analysis of the knee Range of Motion (ROM) in the preoperative phase, at the predischarge visit, and at the follow-up visit for suture removal performed 14 days after surgery. Analysis of PROMs such as: Oxford Knee Score (OKS), Joint Forgotten (JF), NRS score, and SF-12. These questionnaires will be collected in the preoperative phase, at the predischarge visit, and at the follow-up visit for suture removal performed 14 days after surgery. To evaluate whether cryopressotherapy leads to an improvement in predischarge hemoglobin (Hb) levels. To assess whether cryopressotherapy reduces the circumference and subcutaneous fluid accumulation of the operated limb.
CONDITIONS
Official Title
Use of Cryopressotherapy in Patiens Undergoing Total Knee Replacement to Improve Clinical Outcome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Candidates for elective total knee arthroplasty surgery as determined by an orthopedic surgeon
- Aged between 18 and 80 years inclusive
- Body Mass Index (BMI) between 18 and 35 kg/m8
- Willing and able to provide informed consent
- Diagnosed with non-inflammatory degenerative knee joint disease, including osteoarthritis
You will not qualify if you...
- Use of medications that interfere with muscle metabolism
- Presence of bone metastases or diseases at the surgical site
- Presence or suspicion of infection in the knee
- Unable to provide informed consent
- Obesity with BMI equal to or greater than 35 kg/m8
- Need for revision surgery of total knee arthroplasty
- Presence of pacemakers, mechanical implants, or conditions affected by BIA interference
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
IRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Milan 20173
Milan, Italy, Italy, 20157
Actively Recruiting
Research Team
L
Laura Mangiavini
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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