Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06980103

Use of a Decision Aid to Resolve Uncertainty About Radioactive Iodine Treatment in Patients With Intermediate Risk Thyroid Cancer

Led by Georgetown University · Updated on 2026-01-08

408

Participants Needed

3

Research Sites

207 weeks

Total Duration

On this page

Sponsors

G

Georgetown University

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this study is to learn if a decision aid (DA) website helps people with thyroid cancer make informed decisions about radioactive iodine (RAI) treatment. The main questions it aims to answer are: - Does the decision aid help participants understand the risks and benefits of RAI treatment? - Does it help participants make choices that reflect what matters most to them? - How does the decision aid compare to usual care in supporting patients through this decision? Participants who have been recently diagnosed with intermediate-risk differentiated thyroid cancer (DTC) will be randomly assigned to one of two groups. One group will receive a special decision aid website. This site includes detailed information about RAI, short videos, drop-down menus with extra details, exercises to help clarify values, and tools to help patients prepare questions for their doctor. The other group will receive the American Cancer Society (ACS) website. This site gives basic information about RAI but does not include interactive tools and is not specific to intermediate-risk thyroid cancer. Follow up surveys will be sent to the participants periodically, first at the start of the study, and again at 1 week, 4 weeks, and 6 months later. Researchers will compare how the two groups differ in making informed decisions. The decision aid is meant to support, not replace, a conversation with the medical team. Doctor recommendations remain an important part of treatment decisions.

CONDITIONS

Official Title

Use of a Decision Aid to Resolve Uncertainty About Radioactive Iodine Treatment in Patients With Intermediate Risk Thyroid Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 and older
  • Diagnosed with intermediate risk differentiated thyroid cancer less than 6 months ago and currently making a decision about radioactive iodine treatment
  • Able to understand the informed consent information, ask questions, and process answers without cognitive impairment
  • Willing to be contacted and available to complete study activities throughout the study period
Not Eligible

You will not qualify if you...

  • Diagnosis of low risk or high risk differentiated thyroid cancer
  • Prior history of radioactive iodine treatment
  • Clinical reasons preventing consideration of radioactive iodine, such as pregnancy, breastfeeding, or low white blood cell count

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Trial Site Locations

Total: 3 locations

1

Lombardi Comprehensive Cancer Center

Washington D.C., District of Columbia, United States, 20007

Actively Recruiting

2

MedStar Washington Hospital Center

Washington D.C., District of Columbia, United States, 20010

Actively Recruiting

3

Inova Health System

Falls Church, Virginia, United States, 22031

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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