Actively Recruiting

All Genders
NCT04033224

Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure

Led by Careggi Hospital · Updated on 2025-02-12

1000

Participants Needed

15

Research Sites

324 weeks

Total Duration

On this page

Sponsors

C

Careggi Hospital

Lead Sponsor

U

University of Florence

Collaborating Sponsor

AI-Summary

What this Trial Is About

The use of extracorporeal blood purification therapies (EBPT) is becoming increasingly widespread worldwide in everyday clinical practice, particularly in the critical care setting. Nonetheless, most of the clinical trials aimed at exploring the effect of EBPT on patients' long-term outcomes have failed to demonstrate consistent results regarding 28 day- or hospital- mortality rates. The aim of this observational prospective registry is to evaluate if there is a cluster of critically ill patients that mostly benefits from extracorporeal blood purification therapies with different EBPTs.

CONDITIONS

Official Title

Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Critically ill patients in the intensive care unit (ICU)
  • Receiving one of the following EBPT therapies: CRRT, IHD, or hybrid therapies for renal support or replacement
  • Receiving immunomodulation via high cut-off membranes, endotoxin and/or cytokine adsorbent membranes, or high-volume hemofiltration
Not Eligible

You will not qualify if you...

  • Patients treated only with Cytosorb�ae or Toraymyxin�ae therapies

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 15 locations

1

Ospedale S. Giuseppe

Empoli, Firenze, Italy, 50053

Actively Recruiting

2

Ospedale Versilia

Lido di Camaiore, Lucca, Italy, 55049

Actively Recruiting

3

Humanitas Research Hospital

Rozzano, Milano, Italy, 20089

Actively Recruiting

4

IRCCS Policlinico S. Donato

San Donato Milanese, Milano, Italy, 20097

Actively Recruiting

5

Ospedale S. Gerardo

Monza, Monza-Brianza, Italy, 20900

Actively Recruiting

6

Ospedale A. Perrino

Brindisi, Italy, 72100

Actively Recruiting

7

Azienda Ospedaliero Universitaria Careggi

Florence, Italy, 50100

Actively Recruiting

8

Fondazione IRCCS Policlinico San Matteo

Pavia, Italy, 27100

Actively Recruiting

9

Ospedale S. Jacopo

Pistoia, Italy, 51100

Actively Recruiting

10

Ospedale S. Stefano

Prato, Italy, 59100

Actively Recruiting

11

Grande Ospedale Metropolitano "Bianchi Melacrino Morelli"

Reggio Calabria, Italy, 89124

Actively Recruiting

12

Policlinico Universitario Fondazione Agostino Gemelli

Roma, Italy, 00168

Actively Recruiting

13

Azienda Ospedaliero-Universitaria Sant'Andrea

Roma, Italy, 00189

Actively Recruiting

14

Ospedale Maria Vittoria

Torino, Italy, 10144

Actively Recruiting

15

Ospedale S. Bortolo

Vicenza, Italy, 36100

Actively Recruiting

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Research Team

G

Gianluca Villa, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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