Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT07060079

The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease

Led by University College, London · Updated on 2025-07-11

120

Participants Needed

1

Research Sites

74 weeks

Total Duration

On this page

Sponsors

U

University College, London

Lead Sponsor

R

Royal Free Hospital NHS Foundation Trust

Collaborating Sponsor

AI-Summary

What this Trial Is About

Research is being conducted into chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, and bronchiectasis. The investigation specifically focuses on sleep-disordered breathing (SDB) in individuals with chronic respiratory disease. SDB encompasses a range of conditions, the most common of which is obstructive sleep apnoea. In obstructive sleep apnoea, periodic pauses in breathing (apnoea) lead to reduced blood oxygen levels. To detect these events, patients typically undergo sleep studies that involve monitoring oxygen saturation, heart rate, and respiratory patterns during sleep. When chronic respiratory disease and SDB coexist, breathing disturbances during sleep may be exacerbated. To identify SDB, sleep studies are commonly used to assess oxygen levels, heart rate, and breathing patterns. The objective of this research is to identify differences between patients with chronic respiratory diseases who have SDB and those who do not. This will be achieved by analysing sleep study data using a novel analytical approach. The aim is to determine whether this method can yield more detailed insights into the underlying pathophysiology of these conditions.

CONDITIONS

Official Title

The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older with chronic respiratory disease, with or without sleep-disordered breathing
  • Patients who have had previous negative sleep studies to serve as control group
  • Ability to read, understand, and sign the informed consent form
  • Willingness to sleep while using portable monitoring devices
Not Eligible

You will not qualify if you...

  • Under 18 years of age at the time of the study
  • Contraindications to using portable monitoring devices
  • Unable to provide informed consent to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Royal Free hospital

London, United Kingdom, NW3 2QG

Actively Recruiting

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Research Team

N

Nawal Alotaibi

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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