Actively Recruiting
The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease
Led by University College, London · Updated on 2025-07-11
120
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
Sponsors
U
University College, London
Lead Sponsor
R
Royal Free Hospital NHS Foundation Trust
Collaborating Sponsor
AI-Summary
What this Trial Is About
Research is being conducted into chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, and bronchiectasis. The investigation specifically focuses on sleep-disordered breathing (SDB) in individuals with chronic respiratory disease. SDB encompasses a range of conditions, the most common of which is obstructive sleep apnoea. In obstructive sleep apnoea, periodic pauses in breathing (apnoea) lead to reduced blood oxygen levels. To detect these events, patients typically undergo sleep studies that involve monitoring oxygen saturation, heart rate, and respiratory patterns during sleep. When chronic respiratory disease and SDB coexist, breathing disturbances during sleep may be exacerbated. To identify SDB, sleep studies are commonly used to assess oxygen levels, heart rate, and breathing patterns. The objective of this research is to identify differences between patients with chronic respiratory diseases who have SDB and those who do not. This will be achieved by analysing sleep study data using a novel analytical approach. The aim is to determine whether this method can yield more detailed insights into the underlying pathophysiology of these conditions.
CONDITIONS
Official Title
The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older with chronic respiratory disease, with or without sleep-disordered breathing
- Patients who have had previous negative sleep studies to serve as control group
- Ability to read, understand, and sign the informed consent form
- Willingness to sleep while using portable monitoring devices
You will not qualify if you...
- Under 18 years of age at the time of the study
- Contraindications to using portable monitoring devices
- Unable to provide informed consent to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Royal Free hospital
London, United Kingdom, NW3 2QG
Actively Recruiting
Research Team
N
Nawal Alotaibi
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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