Actively Recruiting
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
Led by Trustees of Dartmouth College · Updated on 2025-09-08
15
Participants Needed
1
Research Sites
33 weeks
Total Duration
On this page
Sponsors
T
Trustees of Dartmouth College
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if Therabot-CALM (Cannabis, Anxiety, Low Mood) has acceptability among users and could work to improve the symptoms of persons with cannabis use disorder and anxiety and/or depression. The main question it aims to answer is: What is the usability, feasibility, and acceptability of Therabot-CALM in persons with Cannabis Use Disorder and Anxiety and/or Depression? Participants will * Take a screening questionnaire * Participate in two virtual 1-hour interviews to provide feedback on app design and suggest features. * Engage with Therabot-CALM in a 4-week clinical trial and provide feedback on their app experience in a third virtual interview
CONDITIONS
Official Title
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Is 18 years or older.
- Meet criteria for current Cannabis Use Disorder (CUDIT-R 312) and Major Depressive Disorder (PHQ-9 310), and/or Generalized Anxiety Disorder (GAD-7 310).
- Have reliable access to the internet and a compatible device for Therabot-CALM.
- Have willingness and capacity to provide informed consent and commit to participating in all assessments and interventions during the study.
- Attend the first interview.
You will not qualify if you...
- Moderate to high risk of suicidal thoughts or behaviors as determined by the Columbia-Suicide Severity Rating Scale (C-SSRS) or baseline questionnaires.
- Current psychosis as determined by a brief psychosis screen.
- Current participation in another digital mental health intervention.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
46 Centerra Parkway, Suite 300, Office #333S
Lebanon, New Hampshire, United States, 03766
Actively Recruiting
Research Team
M
Michael V Heinz, MD
CONTACT
A
Amanda C Collins, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DEVICE_FEASIBILITY
Number of Arms
1
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