Actively Recruiting

Phase Not Applicable
Age: 25Years +
FEMALE
Healthy Volunteers
NCT06669533

Use Misoprostol to Optimize Prevention of Cervical Cancer

Led by University of Alabama at Birmingham · Updated on 2025-10-01

420

Participants Needed

1

Research Sites

140 weeks

Total Duration

On this page

Sponsors

U

University of Alabama at Birmingham

Lead Sponsor

C

Cameroon Baptist Convention Health

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a double-blind randomized controlled trial of 420 non-pregnant women undergoing cancer screening by visual inspection with acetic acid (VIA) who have Type 3 transformation zone (TZ) and randomized to receive either Misoprostol or placebo.

CONDITIONS

Official Title

Use Misoprostol to Optimize Prevention of Cervical Cancer

Who Can Participate

Age: 25Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Type 3 transformation zone confirmed on exam prior to randomization
  • Age 25 years or older
Not Eligible

You will not qualify if you...

  • Having Type 1 or 2 transformation zone prior to randomization
  • Currently pregnant
  • History of hysterectomy
  • Any cancerous lesions
  • Active cervicitis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
3
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Trial Site Locations

Total: 1 location

1

Cameroon Baptist Convention Health Core, EtougEbe Baptist Hospital Yaoundé

Yaoundé, Center Region, Cameroon, 2034

Actively Recruiting

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Research Team

W

Warner K Huh, MD

CONTACT

S

Simon M Manga, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

SCREENING

Number of Arms

1

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