Actively Recruiting

Age: 2Years - 99Years
All Genders
NCT05287022

Use of Nasal Nitric Oxide Testing in Improving Primary Ciliary Dyskinesia Clinical Care

Led by Arkansas Children's Hospital Research Institute · Updated on 2025-01-30

150

Participants Needed

1

Research Sites

467 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

this study is aiming at learning more about primary ciliary dyskinesia (PCD) and tests that are used to diagnose this condition. One purpose of this study is to measure the level of nitric oxide in the nasal passages and examine how often the results correlate with other tests currently done to make the diagnosis.

CONDITIONS

Official Title

Use of Nasal Nitric Oxide Testing in Improving Primary Ciliary Dyskinesia Clinical Care

Who Can Participate

Age: 2Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals diagnosed with Primary Ciliary Dyskinesia
  • Individuals with abnormal PCD diagnostic tests (ciliary biopsy or genetic testing)
  • Individuals with unexplained bronchiectasis
  • Individuals undergoing PCD diagnostic testing or having clinical symptoms with at least two of the following: neonatal respiratory distress, organ laterality defects, year-round cough starting in the first year of life, year-round nasal congestion starting in the first year of life, multiple ear infections in the first two years with complications, history of recurrent pneumonias
  • Ability to provide consent by participant or guardian
  • Ability to perform the nasal nitric oxide test
  • Age 2 years or older
Not Eligible

You will not qualify if you...

  • Unable to understand study requirements
  • Unwilling to provide consent
  • Unable to complete the nasal nitric oxide testing
  • Recent sinus surgery within four weeks or recent bloody nose within one week of testing
  • Currently treated with antibiotics for sinusitis or respiratory symptoms within one week
  • Age younger than 2 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Arkansas Children's Hospital

Little Rock, Arkansas, United States, 72202

Actively Recruiting

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Research Team

Z

Zena Ghazala, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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