Actively Recruiting
Use of a New Method for the Microbiological Diagnosis of Severe Corneal Infection
Led by CHU de Reims · Updated on 2024-09-19
46
Participants Needed
1
Research Sites
213 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Microbial keratitis is a severe and often blindness-inducing pathology which represents today the first reason for long-term hospitalization (more than 5 days) in ophthalmology. Its diagnosis is clinical and leads to an immediate hospitalization in the presence of serious criteria (Mackie classification). The entire process of microbiological diagnosis requires several days before etiological confirmation and therefore delays the initiation of targeted therapy. Recently, new PCR systems allowing the detection of 18 to 27 pathogens in 75 minutes have been developed. Their use could thus be transposed to ophthalmology by adapting the microbiological diagnostic technique to samples currently taken by swabbing the cornea. The investigators will compare their diagnosis performance versus conventional methods on patients who suffered for a microbial keratitis with severity criteria.
CONDITIONS
Official Title
Use of a New Method for the Microbiological Diagnosis of Severe Corneal Infection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Over 18 years old
- With social security affiliation
- Willing to participate this study
- Hospitalized in our department for severe infectious keratitis
You will not qualify if you...
- Any prior (48 hours) or concomitant treatment with local or systemic antibiotherapy at time of corneal scrapping and swabbing
- Patient not covered by the French Health Insurance
- Unable to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Damien JOLLY
Reims, France
Actively Recruiting
Research Team
A
Alexandre DENOYER
CONTACT
T
Thomas Ferreira de Moura
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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