Actively Recruiting

Phase 2
Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT06622759

The Use of a Porcine Collagen Matrix for the Prevention of Buccal Bone Wall Resorption During Implant Placement in the Aesthetic Zone.

Led by Aristotle University Of Thessaloniki · Updated on 2025-08-07

36

Participants Needed

1

Research Sites

127 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Aim: To provide a comparative assessment of the clinical and radiographic effect of porcine collagen matrix when placed buccally at the time of single implant placement in the aesthetic zone vs autogenous connective tissue graft in terms of buccal bone resorption and soft tissue augmentation 6 months post operative. Histological assessment and patient reported outcomes were reported

CONDITIONS

Official Title

The Use of a Porcine Collagen Matrix for the Prevention of Buccal Bone Wall Resorption During Implant Placement in the Aesthetic Zone.

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Generally healthy adult patients
  • Age 18 years or older
  • Need for replacement of a single implant in the upper aesthetic zone (second premolar to second premolar)
  • Ridge width (bucco-lingual) no greater than 6 mm at the narrowest point
  • Minimum 2 mm of attached gingiva
  • Ability to maintain good oral hygiene and attend all follow-up visits
  • Ability to understand the surgery and sign informed consent
Not Eligible

You will not qualify if you...

  • Poor oral hygiene (FMPS < 20%, FMBS < 15%) and poor motivation
  • Smoking more than 10 cigarettes per day
  • Need for bone augmentation
  • Untreated periodontitis
  • General contraindications for dental or surgical treatment
  • History of cancer or related treatments within past 5 years
  • Women of childbearing age not using accepted contraception
  • Pregnancy or breastfeeding
  • Current use of medications affecting mucosal healing
  • Diseases affecting connective tissue metabolism
  • Allergy to collagen

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Preventive Dentistry, Periodontology &amp; Implant Biology, School of Dentistry, Aristotle University

Thessaloniki, Thessaloniki, Greece, 54124

Actively Recruiting

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Research Team

I

Ioannis Vouros, DDS, Ph.D

CONTACT

L

Louiza Papantonatou, DDS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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