Actively Recruiting
Use of Sensory Substitution to Improve Arm Control After Stroke
Led by Marquette University · Updated on 2025-09-29
30
Participants Needed
1
Research Sites
149 weeks
Total Duration
On this page
Sponsors
M
Marquette University
Lead Sponsor
M
Medical College of Wisconsin
Collaborating Sponsor
AI-Summary
What this Trial Is About
Supplementing or augmenting sensory information to those who have lost proprioception after stroke could help improve functional control of the arm. Thirty subjects will be recruited to a single site to evaluate the ability of supplemental kinesthetic feedback (a form of vibrotactile stimulation) to improve motor function. Participants will be tested in performing reaching movements as well as more functional tasks such as simulated drinking from a glass
CONDITIONS
Official Title
Use of Sensory Substitution to Improve Arm Control After Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Stroke survivors who can perform stabilization and grip modulation tasks
- Had a single ischemic or hemorrhagic stroke of the middle cerebral artery in the chronic recovery phase (> 6 months post-stroke)
- Ability to give informed consent and follow two-stage instructions
- Mild-to-moderate motor impairment of the affected arm, with a Fugl-Meyer upper extremity score between 28 and 50 inclusive
- Proprioceptive deficit at the elbow of the more involved arm
- Preserved tactile sensation in the unaffected arm and/or thigh
- Minimal active wrist extension of 5 degrees or more
You will not qualify if you...
- Inability to give informed consent or follow two-stage instructions
- Bleeding disorders
- Fixed contractures or history of tendon transfer in the affected limb
- Diagnosis of myasthenia gravis, amyotrophic lateral sclerosis, or other diseases affecting neuromuscular function
- Current use or influence of aminoglycoside antibiotics, curare-like agents, or other neuromuscular interfering drugs
- History of epilepsy
- Psychiatric co-morbidities such as schizophrenia
- Malignant or benign intra-axial brain tumors
- Concurrent illness limiting ability to comply with study requirements
- Cardiac pacemaker, arrhythmia, or significant cardiovascular or respiratory problems
- Profound muscle atrophy or excessive weakness in target testing areas
- Systemic infection
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Marquette University
Milwaukee, Wisconsin, United States, 53233
Actively Recruiting
Research Team
R
Robert A Scheidt, PhD
CONTACT
K
Kimberly D Bassindale, DPT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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