Study of Sublingual Melatonin to Reduce Anxiety During Cataract Surgery in Older Adults

What this Trial Is About

This research evaluates the use of sublingual melatonin as a premedication to reduce anxiety and improve sedation in older adults undergoing cataract surgery. The study focuses on comparing the effects of melatonin with a placebo in elderly patients, aiming to maintain safety and minimize changes in blood pressure and heart rate during surgery. Participants are randomly assigned to receive either a 6 mg sublingual melatonin tablet or a placebo tablet one hour before their cataract surgery. Both tablets look identical to maintain blinding. The study involves local anesthesia for the surgery, and the melatonin is given in a form that dissolves quickly under the tongue to ensure proper absorption. During the study, anxiety levels are measured at multiple times before and after the procedure, including 30 and 60 minutes before surgery, during anesthesia application, and 15 and 30 minutes after anesthesia. The study also monitors sedation levels and any hemodynamic changes. Participants complete questionnaires and undergo assessments to provide data on the effects of melatonin compared to placebo, with safety being closely watched throughout the trial.

The Use of Sublingual Melatonin Premedication in Geriatric Cataract Surgery