Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT04732052

The Use of Transcranial Direct Current Stimulation (tDCS) in Adults With Developmental Disabilities

Led by Dr. Najat Khalifa · Updated on 2025-03-25

60

Participants Needed

1

Research Sites

330 weeks

Total Duration

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AI-Summary

What this Trial Is About

Aggressive behaviours are highly prevalent among people with developmental disabilities, both in community and inpatient or residential settings, with adverse consequences for the individuals involved and others. Some predictive factors, particularly impulsivity, are dynamic with neurobiological underpinnings, and as such amenable to change or neuromodulation using non-invasive brain stimulation techniques. With this in mind, we designed an experimental protocol to determine the efficacy of transcranial Direct Current Stimulation (tDCS) as a non-invasive brain stimulation technique to reduce impulsivity and aggression associated with developmental disability.

CONDITIONS

Official Title

The Use of Transcranial Direct Current Stimulation (tDCS) in Adults With Developmental Disabilities

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18-64 years
  • Diagnosis of a developmental disability
  • History of one or more incidents of aggression in the last month
  • Consent to participate in the trial by the individual or their Substitute Decision Maker
Not Eligible

You will not qualify if you...

  • History of epilepsy or seizures
  • History of acquired brain injury
  • Having metal in the brain/skull, e.g. splinters, fragments or clips
  • Having a cochlear implant
  • Having an implanted neuro-stimulator (e.g. direct brain stimulation, epidural/subdural stimulation, vagal nerve stimulation)
  • History of brain surgery of procedure
  • History of severe adverse reaction to tDCS
  • Having a cardiac pacemaker or intracardiac lines
  • Current alcohol or drug misuse
  • Having a sensitive scalp

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Providence Care Hospital

Kingston, Ontario, Canada, K7L 4X3

Actively Recruiting

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Research Team

N

Najat Khalifa, MD

CONTACT

A

Andrew Bickle, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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