Actively Recruiting
Usefulness of ICG Angiography-Guided Thyroidectomy for Preserving Parathyroid Function
Led by Hospital Universitari de Bellvitge · Updated on 2025-03-19
394
Participants Needed
2
Research Sites
168 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Transient and/or permanent hypoparathyroidism is the most frequent complication after total thyroidectomy. The identification of the parathyroid glands and a correct dissection during thyroidectomy have been postulated as key factors for their preservation and, consequently, to prevent hypoparathyroidism. The use of indocyanine green (ICG) fluorescence has reliably predicted parathyroid glands functionality in the immediate postoperative period. Recently, it is proposed that showing the vascular map of the parathyroid glands before performing the thyroidectomy by means of ICG angiography prevent the development of postoperative hypoparathyroidism. The goal of this multicentric study is to demonstrate that the preservation of the function of parathyroid glands is greater with use of arteriography than without. Patients will be divided in two groups. In the study group, the vascular map with ICG of parathyroid glands will be showed before performing the lobectomy. Once the lobectomy is done, the function of the glands will be assessed. Whereas in the control group, arteriography with ICG will only be carried out in order to check their function at the end of the lobectomy. Researchers will compare the study group and the control group to see which one present the lowest taxes of postoperative hypoparathyroidism.
CONDITIONS
Official Title
Usefulness of ICG Angiography-Guided Thyroidectomy for Preserving Parathyroid Function
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 18 years of age or older with a surgical indication for total thyroidectomy with or without central cervical lymph node dissection due to thyroid disease
- Ability to understand the study and provide informed consent
You will not qualify if you...
- Previous surgery on the thyroid or parathyroid glands
- Hyperparathyroidism requiring parathyroidectomy during the same surgery
- Contraindications to indocyanine green (ICG) administration
- Current drug use or alcohol abuse interfering with study compliance
- Participation in other drug trials within one month prior to randomization
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Hospital UIniversitari de Bellvitge
L'Hospitalet de Llobregat, Barcelona, Spain, 08907
Actively Recruiting
2
Pablo Moreno Llorente
L'Hospitalet de Llobregat, Barcelona, Spain, 08907
Actively Recruiting
Research Team
P
Pablo Moreno
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
PREVENTION
Number of Arms
2
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