Actively Recruiting

Age: 18Years +
All Genders
NCT05688592

Usefulness of PET-CT for Invasive Fungal Infection

Led by Puerta de Hierro University Hospital · Updated on 2024-11-06

224

Participants Needed

14

Research Sites

83 weeks

Total Duration

On this page

Sponsors

P

Puerta de Hierro University Hospital

Lead Sponsor

G

Gilead Sciences

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this national multicenter prospective cohort study is to learn about the added value of 18F-FDG (18F-2-fluoro-2-deoxy-D-glucose) PET-CT in invasive fungal disease management. The main questions it aims to answer are: 1. Does the use of 18F-FDG PET-CT allow a better characterization of invasive fungal infection (IFI) (performance) compared to the exclusive use of conventional radiological studies in terms of extension/staging and monitoring of response/follow-up ? 2. Does the systematic and protocolized use of 18F-FDG PET-CT in IFI allow a better management of patients with IFI and increase the prognostic value of the initial evaluation? Participants will undergo systematically a 18F-FDG PET-CT as part of the work-up of their invasive fungal disease. Researchers will compare the performance of 18F-FDG PET-CT with standard management without 18F-FDG PET-CT to see if adds value (diagnostic, prognostic, and changes in management).

CONDITIONS

Official Title

Usefulness of PET-CT for Invasive Fungal Infection

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 years or older
  • Admitted with a diagnosis of invasive fungal infection
  • Able to undergo one 18F-FDG PET-CT scan
  • Provided informed consent to participate
Not Eligible

You will not qualify if you...

  • Presence of active bacterial infection that may affect organ or tissue uptake
  • Recent surgery in the area of invasive fungal infection within the past 3 months
  • Medical conditions interfering with study participation (e.g., inability to tolerate the test, pregnancy)
  • Terminal illness or condition

AI-Screening

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Trial Site Locations

Total: 14 locations

1

Hospital Universitario Puerta de Hierro

Majadahonda, Madriid, Spain, 28222

Actively Recruiting

2

Hospital de Bellvitge

Barcelona, Spain

Actively Recruiting

3

Hospital Universitario Clinic

Barcelona, Spain

Actively Recruiting

4

Hospital Universitario Virgen de las Nieves

Granada, Spain

Actively Recruiting

5

Hospital Infanta Leonor Hospital

Madrid, Spain

Actively Recruiting

6

Hospital Universitario Gregorio Marañón

Madrid, Spain

Actively Recruiting

7

Hospital Universitario La Paz

Madrid, Spain

Actively Recruiting

8

Hospital Unversitario Ramón y Cajal

Madrid, Spain

Actively Recruiting

9

Hospital Virgen de la Victoria

Málaga, Spain

Actively Recruiting

10

Hospital Morales Messeguer

Murcia, Spain

Not Yet Recruiting

11

Hospital Virgen de la Arrixaca

Murcia, Spain

Not Yet Recruiting

12

Hospital Universitario Central de Asturias

Oviedo, Spain

Actively Recruiting

13

Hospital Unversitario de Salamanca

Salamanca, Spain

Actively Recruiting

14

Hospital Universitario Virgenn de la Macarena

Seville, Spain

Actively Recruiting

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Research Team

A

Andrea Gutiérrez Villanueva, MD

CONTACT

B

Begoña Rodríguez Alfonso, MDPhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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