Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07191795

Uses of Phantom Sensations Induced by Global and Local Modifications of the Prosthetic Socket as Somatosensory Feedback During Walking in Lower Limb Amputees

Led by Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est · Updated on 2025-09-25

228

Participants Needed

1

Research Sites

315 weeks

Total Duration

On this page

Sponsors

U

Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est

Lead Sponsor

C

Clinique Chantecler

Collaborating Sponsor

AI-Summary

What this Trial Is About

Following lower-limb amputation, the loss of somatosensory information from the missing limb renders walking less automatic, more cognitively demanding, and often asymmetric, which can lead to secondary pathologies. Hypothesis: This study is based on the hypothesis that phantom limb sensations (PLS), when coherent with the prosthetic device's movements and the phases of the gait cycle, can compensate for the loss of somatosensory feedback and thereby improve locomotion for individuals with amputation. It is further hypothesized that it is possible to artificially induce these coherent and useful sensations, notably through "referred sensations" elicited by stimulation of the residual limb (e.g., via the prosthetic socket). Objectives: The project aims to: * Determine whether the natural presence of phantom limb sensations during walking impacts gait parameters. * Confirm in a larger patient population that modifications to the prosthetic socket can induce or enhance phantom sensations that are perceived as useful for walking. * Investigate whether these perceptual changes (induced or enhanced) are associated with objective, measurable improvements in gait quality.

CONDITIONS

Official Title

Uses of Phantom Sensations Induced by Global and Local Modifications of the Prosthetic Socket as Somatosensory Feedback During Walking in Lower Limb Amputees

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants with major lower limb amputation
  • Ability to understand and express oneself in French
  • Affiliated with a social security scheme
  • Asymptomatic volunteers with no major lower limb surgery in the past 3 years
  • No minor injuries affecting walking in the past year for volunteers
Not Eligible

You will not qualify if you...

  • History of psychiatric disorders
  • Pregnant or breastfeeding women
  • Minors
  • Adults under legal protection or guardianship
  • Pain affecting walking (including trunk, residual limb, phantom limb, or opposite limb)
  • Medical treatments that prevent walking

AI-Screening

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Trial Site Locations

Total: 1 location

1

Institut Régional de Médecine Physique et de Réadaptation

Nancy, France, 54000

Actively Recruiting

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Research Team

J

Jonathan J Pierret, PhD

CONTACT

C

Christelle C Requena

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

3

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