Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT07493213

USG-Guided Shoulder Injections in Frozen Shoulder

Led by Konya Beyhekim Training and Research Hospital · Updated on 2026-05-14

68

Participants Needed

1

Research Sites

65 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Frozen shoulder (adhesive capsulitis) is characterized by pain and a progressive restriction of both active and passive shoulder range of motion, significantly impairing daily activities and quality of life. This study aims to evaluate the effectiveness of USG-guided shoulder injections, when added to a home-based exercise program, in the conservative management of patients with chronic, painful frozen shoulder. In this prospective randomized study, patients diagnosed with painful frozen shoulder will be included. In addition to a standardized home-based exercise program, patients will receive either USG-guided suprascapular nerve block alone or a combination of suprascapular nerve block and subacromial injection. The effects of these approaches on clinical outcomes will be assessed over a 20-week follow-up period. Primary outcome measures include pain intensity assessed by the Visual Analog Scale (VAS), functional status evaluated by the Shoulder Pain and Disability Index (SPADI), and shoulder range of motion. Secondary outcomes include depression level (Beck Depression Inventory), sleep quality, pain phenotype (nociplastic, neuropathic, or nociceptive), hand grip strength, ultrasonographic findings ( (coracohumeral ligament thickness, subacromial bursa thickness) , and patient satisfaction (subjective impression of improvement). The results of this study are expected to provide evidence on the comparative effectiveness and additional benefits of different shoulder injection approaches when combined with home-based exercise therapy in patients with chronic frozen shoulder.

CONDITIONS

Official Title

USG-Guided Shoulder Injections in Frozen Shoulder

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

Age between 18 and 75 years and willingness to participate in the study

Presence of shoulder pain lasting at least 3 months and a diagnosis of primary frozen shoulder

Pain intensity ≥ 4/10 on the Visual Analog Scale (VAS), resistant to medical treatment/analgesics

Restriction of ≥30 degrees in at least two planes of shoulder motion (flexion, abduction, or external rotation)

-

Not Eligible

You will not qualify if you...

  • History of shoulder trauma

Presence of neurological conditions such as stroke, brachial plexus injury, Parkinson's disease, or cervical spine pathology with or without radiculopathy

History of shoulder surgery, shoulder malignancy or tumor, or prior shoulder manipulation

Presence of shoulder arthritis, rotator cuff tear, other shoulder injuries, or thoracic outlet syndrome

Systemic diseases affecting the shoulder, severe degeneration or trauma (e.g., osteoarthritis, rheumatoid arthritis, labral or articular cartilage injuries), or inflammatory rheumatic diseases

Steroid injection to the affected extremity within the last 3 months, use of oral steroids or NSAIDs, or ongoing surgical/interventional treatment

Pregnancy or lactation

Uncontrolled diabetes, heart failure, or uncontrolled systemic diseases (e.g., liver failure, chronic kidney disease, significant endocrine disorders)

Communication problems or severe psychiatric disorders

AI-Screening

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Trial Site Locations

Total: 1 location

1

Konya Beyhekim Training and Research Hospital

Konya, Selçuklu, Turkey (Türkiye), 42000

Actively Recruiting

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Research Team

F

Fulya Ece URKAN, MD

CONTACT

İ

İsmail urkan, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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