Actively Recruiting
Using Antibiotics to Prevent Infections in Hemodialysis Patients During Catheter Placement
Led by Western Galilee Hospital-Nahariya · Updated on 2025-02-07
200
Participants Needed
1
Research Sites
191 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine if prophylactic antibiotic treatment can reduce the incidence of early catheter-related infections in hemodialysis patients at high risk, including those with femoral catheter placement, atrial fibrillation, or heart failure. The main questions it aims to answer are: 1. Will prophylactic antibiotic administration reduce catheter-related infections by 50% within 45 days of catheter insertion? 2. Will this intervention decrease the rate of secondary complications such as metastatic infections, cardiovascular morbidity, and mortality? Researchers will compare patients receiving prophylactic antibiotics (e.g., cefamezine and gentamicin, or vancomycin for high-risk individuals) to those not receiving antibiotics, to assess the difference in infection rates and associated complications. Participants : * Be randomized into two groups: one receiving prophylactic antibiotics and one without antibiotics before catheter placement or replacement. * Undergo follow-up for 45 days to monitor for catheter-related infections and secondary complications. This study will provide critical data to evaluate whether targeted prophylactic antibiotic treatment should become standard practice for high-risk hemodialysis patients.
CONDITIONS
Official Title
Using Antibiotics to Prevent Infections in Hemodialysis Patients During Catheter Placement
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hemodialysis patients scheduled for new tunneled catheter placement or replacement of an existing tunneled catheter.
- Prior diagnosis of at least one of the following: atrial fibrillation, heart failure, or femoral tunneled catheter.
- Patients who have signed informed consent to participate in the study.
You will not qualify if you...
- Hemodialysis patients unable to provide informed consent and requiring a legal guardian.
- Patients undergoing prolonged antibiotic therapy prior to tunneled catheter insertion.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Galilee Medical Center
Nahariya, Israel, Israel, 2210001
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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