Actively Recruiting
Using a Blood Test and Software Tool to Guide Treatment for Venous Thromboembolism
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-05-05
259
Participants Needed
8
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to find out whether a software tool, ctDNA/VTE (Venous Thromboembolism) risk score model, is an effective way to predict the likelihood of VTE coming back in people who have received anticoagulant treatment.
CONDITIONS
Official Title
Using a Blood Test and Software Tool to Guide Treatment for Venous Thromboembolism
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 or older with a history of cancer-associated VTE confirmed by imaging
- Completion of 3 to 12 months of anticoagulation treatment with enoxaparin, dalteparin, rivaroxaban, or apixaban without current VTE symptoms
- Diagnosis of solid tumors in advanced stage or receiving systemic anticancer treatment within six weeks of enrollment, including breast, hepatobiliary, prostate, non-small cell lung, pancreatic, or bladder cancer
- Signed and dated informed consent by participant or legally authorized representative
You will not qualify if you...
- Contraindication to ongoing or discontinuation of anticoagulation
- History of major bleeding in the last six months
- Known disseminated intravascular coagulation (DIC)
- Suspicion of tumor thrombus on imaging at original VTE diagnosis
- Enrollment in hospice care
- Current inferior vena cava (IVC) filter
- Diagnosis of an active hematologic malignancy
AI-Screening
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Trial Site Locations
Total: 8 locations
1
Memorial Sloan Kettering Cancer Center Basking Ridge (All Protocol Activities)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
2
Memorial Sloan Kettering Monmouth (All Protocol Activities)
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering Bergen (All Protocol Activities)
Montvale, New Jersey, United States, 07645
Actively Recruiting
4
Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities)
Commack, New York, United States, 11725
Actively Recruiting
5
Memorial Sloan Kettering Westchester (All Protocol Activities)
Harrison, New York, United States, 10604
Actively Recruiting
6
Memorial Sloan Kettering Cancer Center (All Protocol Activites)
New York, New York, United States, 10065
Actively Recruiting
7
Memorial Sloan Kettering Nassau (All protocol activities)
Rockville Centre, New York, United States, 11553
Actively Recruiting
8
Royal North Shore Hospital, Australia
Sydney, Australia, 2065
Not Yet Recruiting
Research Team
J
Justin Jee, MD, PhD
CONTACT
J
Jeffrey Zwicker, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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