Actively Recruiting

Phase 4
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT06741358

Using Glialia for Treating Persistent Perceptual Postural Dizziness

Led by I.R.C.C.S. Fondazione Santa Lucia · Updated on 2025-11-20

30

Participants Needed

1

Research Sites

94 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This pilot study will involve 30 participants recruited from the Santa Lucia Foundation IRCCS, including 20 patients diagnosed with Persistent Perceptual Postural Dizziness (PPPD), and might or might not have previously contracted Sars Cov2 infection. They who will be randomly assigned to receive either the Glialia supplement or placebo. Additionally, 10 control participants who have recovered from COVID-19 will receive Glialia to help assess the influence of previous COVID-19 infection on neuroinflammation levels. The study aims to compare baseline neuroinflammation levels between PPPD patients and controls, measure changes in neuroinflammation in all groups after treatment and to determine if the reduction in neuroinflammation is more significant in the Glialia group compared to the placebo group. The trial will be conducted in a triple-blind manner, ensuring that neither participants nor researchers know the treatment assignments. Each participant will receive sachets to be taken daily for 60 days, with the study providing both the Glialia supplement and placebo at no cost.

CONDITIONS

Official Title

Using Glialia for Treating Persistent Perceptual Postural Dizziness

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 65 years
  • Diagnosis of Persistent Perceptual Postural Dizziness (PPPD) for PPPD groups
  • Recovery from COVID-19 infection or absence of previous infection for PPPD groups
  • Previous COVID-19 infection for control group
Not Eligible

You will not qualify if you...

  • Presence of other neurological and ear-related disorders besides PPPD for PPPD groups
  • Pregnancy
  • Presence of neurological and ear-related disorders for control group

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fondazione Santa Lucia IRCCS

Rome, RM, Italy, 00142

Actively Recruiting

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Research Team

I

Iole Indovina, PhD

CONTACT

D

Diego Piatti, PT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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Using Glialia for Treating Persistent Perceptual Postural Dizziness | DecenTrialz