Actively Recruiting
Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History
Led by University of Southern California · Updated on 2025-08-01
112
Participants Needed
1
Research Sites
207 weeks
Total Duration
On this page
Sponsors
U
University of Southern California
Lead Sponsor
D
Duke University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This double-blind, randomized, crossover trial aims to test the hypothesis that longer-term indoor air filtration intervention can slow atherothrombosis progression by reducing indoor fine particulate matter (PM2.5) exposure in adults with ischemic heart disease history.
CONDITIONS
Official Title
Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 65 and 84 years old
- Weigh at least 110 pounds
- Nonsmoker for at least 1 year
- History of ischemic heart disease, clinically stable for 6 months without worsening symptoms or angina episodes
- Able to speak English or Spanish
- Live in Los Angeles County
You will not qualify if you...
- History of degenerative nervous system diseases such as dementia or Alzheimer's
- Currently undergoing active cancer treatment
- Home already has HEPA filters installed
- Planning to move away from current residence within 2 years
- Expect to spend more than 1 month living outside the primary home
- Health conditions that prevent collection of health data and biospecimens
- Home is not suitable for placing air purifiers and pollution monitors
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Keck School of Medicine, University of Southern California
Los Angeles, California, United States, 90033
Actively Recruiting
Research Team
Z
Zhanghua Chen, PhD
CONTACT
J
Junfeng Zhang, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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