Actively Recruiting
Using MRI To Detect Soft Tissue Reactions And Implant Integration As Related To Implant Modularity
Led by Hospital for Special Surgery, New York · Updated on 2025-06-19
240
Participants Needed
1
Research Sites
463 weeks
Total Duration
On this page
Sponsors
H
Hospital for Special Surgery, New York
Lead Sponsor
M
Medical College of Wisconsin
Collaborating Sponsor
AI-Summary
What this Trial Is About
Patients with a total hip replacement may require early revision surgery due to an adverse local tissue reaction or bone resorption that occurs due to wear debris released from the implant. MRI provides a non-invasive biomarker for clinicians and surgeons to detect early adverse synovial reactions which may exist in the absence of clinical symptoms, thus imparting essential information for clinical management. This study will address two of the most commons causes of hip implant failure, including adverse local tissue reaction in implants not traditionally associated with adverse tissue reactions, as well as the presence of aseptic loosening and loss of implant-bone integration.
CONDITIONS
Official Title
Using MRI To Detect Soft Tissue Reactions And Implant Integration As Related To Implant Modularity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have a total hip replacement with a ceramic component undergoing revision for any reason, including recurrent dislocation
- Have a metal-on-polyethylene total hip replacement and have repeated dislocation
- Have a metal-on-polyethylene total hip replacement greater than 1 year old
- Have an infected total hip replacement (any surface bearing)
- Have a total hip replacement with a ceramic component
- Have a metal-on-polyethylene total hip replacement
- Have your original or revised total hip replacement
You will not qualify if you...
- Have occupational exposure to cobalt or chromium
- Presence of metal-on-metal or recalled implant
- Have had a prior revision of your total hip
- Standard contraindications to MRI
- Have cemented components
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital for Special Surgery
New York, New York, United States, 10021
Actively Recruiting
Research Team
M
Matthew F Koff, PhD
CONTACT
M
Mauro Miranda, MFA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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