Actively Recruiting
Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life
Led by University of Chicago · Updated on 2026-03-04
60
Participants Needed
1
Research Sites
250 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this research is to gather information on the safety and effectiveness of using an imaging technique called magnetic resonance imaging (MRI) to decrease radiation dose to the uninvolved prostate (areas of the prostate that do not clearly have cancer cells) while increasing radiation dose to the nodules (hardened areas of the prostate that have cancer cells).
CONDITIONS
Official Title
Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male patients aged 18 years or older with an ECOG Performance Status of 0 to 2
- Histologically confirmed prostate adenocarcinoma visible on MRI
- Prostate cancer classified as intermediate- or high-risk according to NCCN guidelines
- No spread of cancer outside the pelvis
You will not qualify if you...
- Presence of distant metastases
- Prior active treatment for prostate cancer, including surgery, high-intensity focused ultrasound, cryosurgery, hormone therapy, or chemotherapy
- Previous pelvic radiation therapy including brachytherapy
- Active concurrent cancers, except localized skin squamous or basal cell carcinoma
- Medical conditions preventing safe treatment with radiation or hormone therapy
- Contraindications to MRI such as metal implants, allergy to contrast, impaired kidney function, or inability to tolerate MRI
- Use of hydrogel or hyaluronic acid spacers
- Inability to give informed consent
- Inability to follow study protocols
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Chicago Medicine Comprehensive Cancer Center
Chicago, Illinois, United States, 60637
Actively Recruiting
Research Team
C
Clinical Trials Intake
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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