Actively Recruiting

Phase Not Applicable
Age: 12Years - 17Years
All Genders
NCT07269353

Using Neurotechology to Help Children With Physical Disability Due to Cerebral Palsy

Led by University of Alberta · Updated on 2026-02-09

8

Participants Needed

1

Research Sites

86 weeks

Total Duration

On this page

Sponsors

U

University of Alberta

Lead Sponsor

A

Alberta Health services

Collaborating Sponsor

AI-Summary

What this Trial Is About

Hemiparetic cerebral palsy is a condition in which one side of a child's body becomes weak due to brain injury occurring around birth, often caused by stroke. Weakness on the affected side reduces the ability to use the involved hand and arm, limiting everyday activities such as dressing, eating, and playing. Few effective treatments currently exist, especially for children with severe weakness. The study described here examines a new therapy that combines Brain-Computer Interface (BCI) technology with Functional Electrical Stimulation (FES). BCI technology uses brain signals to control external devices; in this therapy, brain signals activate muscles through electrical stimulation. When a child imagines wrist movement, the system detects the associated brain activity and delivers electrical stimulation to generate actual movement. Such paired activity supports neural rewiring and strengthens connections between the brain and muscles, leading to improved arm function. Previous research demonstrates strong benefits of BCI-FES for adults after stroke, but minimal testing has been conducted with children. The current study will evaluate whether BCI-FES improves arm and hand function in children aged 12 to 17 with hemiparetic cerebral palsy. Participants will complete 15 to 20 sessions over a two-month period while wearing a cap that records brain signals. During each session, the system provides muscle stimulation and visual feedback through animated hand movements. Outcome measures will include performance of daily tasks, hand dexterity, muscle activity, and the presence of any adverse effects. The overarching goal is to create a fun, engaging, and effective therapy that supports recovery of hand use and greater independence. Successful results could guide larger studies and inspire new technology-based treatments that enhance quality of life for children with cerebral palsy.

CONDITIONS

Official Title

Using Neurotechology to Help Children With Physical Disability Due to Cerebral Palsy

Who Can Participate

Age: 12Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinically confirmed moderate to severe hemiparetic cerebral palsy with goals to improve wrist extension
  • Age between 12 and 17 years
  • Informed consent or assent provided
  • Normal corrected vision and hearing
  • Ability to maintain supported sitting for at least 30 minutes
Not Eligible

You will not qualify if you...

  • Bilateral perinatal stroke
  • No motor strength in wrist extension
  • Severe hemiparesis (MACS level V)
  • Severe developmental delay or inability to follow study procedures
  • Severe wrist contractures limiting wrist extension
  • Upper extremity orthopedic surgery or botulinum toxin treatment within past 6 months
  • Initial BCI system classification accuracy below significance level

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Glenrose Rehabilitation Hospital

Edmonton, Alberta, Canada, T5G 0B7

Actively Recruiting

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Research Team

E

Ephrem Zewdie, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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