Actively Recruiting
Using ROSA for Challenging The TKA Standard of Care
Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2025-05-14
90
Participants Needed
1
Research Sites
84 weeks
Total Duration
On this page
Sponsors
L
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lead Sponsor
Z
Zimmer Biomet
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a prospective, randomized controlled trial using the cruciate retaining, MC Persona to comparing the conventional TKA to ROSA assisted TKA. Patients will be randomized to one of three study trial arms. 1. Standard of care medial parapetallar approach (Control) 2. ROSA PSA medial parapetallar approach 3. ROSA PSA medial subvastus approach Participants will be followed for 1 year post surgery with a combination of perioperative parameters, imaging, patient reported outcomes, functional outcomes, blood and tissue sampling for inflammatory information and activity levels.
CONDITIONS
Official Title
Using ROSA for Challenging The TKA Standard of Care
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Symptomatic osteoarthritis of the knee indicating primary total knee arthroplasty
- Varus knee deformity of 0 to 10 degrees
- Sufficient ligamentous function to warrant retention of the posterior cruciate ligament
- Between the ages of 21 and 80 inclusive
- Patients willing and able to comply with follow-up requirements and self-evaluations
- Ability to give informed consent
You will not qualify if you...
- Active or prior infection
- Medical condition precluding major surgery
- Predominantly inflammatory arthropathy
- Patellectomy
- Posterior cruciate ligament deficiency
- Major coronal plane deformity
- Prior trauma to the tibia or femur causing malalignment, canal occlusion, or requiring open reduction and internal fixation
- Valgus alignment
- Neurologic condition limiting mobility
- Bone defects needing augments, cones, or stemmed implants
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University Hospital
London, Ontario, Canada
Actively Recruiting
Research Team
L
Lyndsay Somerville, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
3
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