Actively Recruiting
Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors
Led by UNC Lineberger Comprehensive Cancer Center · Updated on 2026-03-23
240
Participants Needed
1
Research Sites
157 weeks
Total Duration
On this page
Sponsors
U
UNC Lineberger Comprehensive Cancer Center
Lead Sponsor
V
Virginia Commonwealth University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The AYA WELL study is a 2-arm randomized clinical trial to test the efficacy of a theory-based, mHealth weight management intervention adapted specifically for adolescent and young adult cancer survivors compared to a self-guided arm. Participants, diagnosed with cancer between ages 15-39, currently age 18-39, post-treatment at least 6 months, and who have overweight or obesity will be randomized to receive either: 1) a comprehensive mHealth weight management program (intervention) or 2) digital tools + health education + peer support (self-guided) over 12 months. Outcomes will be assessed at 3, 6, and 12 months.
CONDITIONS
Official Title
Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between 18 and 39 years old at the time of consent
- Diagnosed with first invasive cancer between ages 15 and 39 years (self-report)
- Within 10 years of diagnosis with no progressive disease or second primary cancers (self-report)
- Completed active cancer treatment at least 6 months before enrollment; maintenance therapy allowed
- Have a body mass index (BMI) between 25 and 50 kg/m2
You will not qualify if you...
- Have type 1 diabetes or receive certain treatments for type 2 diabetes
- History of heart attack or stroke within the last 6 months
- Health problems preventing walking or positive responses to PAR-Q items about heart problems, chest pains, faintness, or dizziness
- Lost 5% or more body weight and kept it off in the last 3 months
- History of eating disorders or recent compensatory behaviors
- Currently pregnant, pregnant in the past 6 months, or planning pregnancy in next 12 months
- Untreated thyroid disease or recent changes in thyroid medication
- Hospitalized for depression or psychiatric disorder within past 12 months
- History of psychotic disorder or uncontrolled bipolar disorder
- Participating in other weight, nutrition, or physical activity studies
- Using prescription medications affecting weight or appetite (except stable SSRIs)
- History of or planned weight loss surgery
- Unable to speak or read English
- Not living in the United States
- No mobile phone with data plan or unwilling to receive study texts
- No internet access
- Not willing to be randomized to either intervention group
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States, 27514
Actively Recruiting
Research Team
M
Molly Diamond, MPH
CONTACT
K
Karen E. Hatley, MPH, RD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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