Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT07557706

Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

Led by University of Alabama at Birmingham · Updated on 2026-04-29

24

Participants Needed

1

Research Sites

67 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help improve how the body regulates heart rate and blood pressure in people with Parkinson's Disease (PD). Problems with heart rate and blood pressure control are common and can make it harder for people to exercise or do daily activities. By using this non-invasive form of nerve stimulation and testing how it affects the body's natural responses, this study hopes to learn if taVNS could be a helpful tool to support physical therapy and improve overall function.

CONDITIONS

Official Title

Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of idiopathic Parkinson's Disease
  • Stable medication for at least 4 weeks prior to the study
  • Age between 18 and 80 years
Not Eligible

You will not qualify if you...

  • Use of beta blockers
  • Sustained severe hypertension (>= 180/110 mmHg while seated)
  • Significant uncontrolled cardiac arrhythmia
  • Unstable angina
  • Congestive heart failure
  • History of myocardial infarction
  • History of seizures
  • Severe cognitive impairment
  • Pregnant women or women planning to become pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Wellness, Health and Research Facility at UAB

Birmingham, Alabama, United States, 35209

Actively Recruiting

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Research Team

A

Alexandra Evancho, DPT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

2

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Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease | DecenTrialz