Actively Recruiting
Using TMS to Understand Neural Processes of Social Motivation
Led by Auburn University · Updated on 2026-03-03
40
Participants Needed
1
Research Sites
200 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to use transcranial magnetic stimulation (TMS) to better understand the neural circuits associated with social motivation. Participant includes four study visits each that range from 1.5 - 3.0 hours in duration over approximately a one month period. The first study visit involves answering survey questions, a clinical interview, and computer tasks. The second study visit involves a magnetic resonance imaging (MRI) scan, computer tasks, and a brief TMS protocol. The second and third study visits involve a full session of TMS followed by an MRI scan and computer tasks. Adults in the Auburn/Opelika area and surrounding areas who avoid social situations, experience symptoms of depression or social anxiety, and are between 25 years old and 50 years old are eligible to participate.
CONDITIONS
Official Title
Using TMS to Understand Neural Processes of Social Motivation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- A diagnosis of Major Depressive Disorder OR a diagnosis of Social Anxiety Disorder (assessed/confirmed at screening visit)
- Scoring above clinical threshold on a measure of social avoidant behavior (assessed/confirmed at phone screen)
You will not qualify if you...
- Unstable psychotropic medication regimen (changes in medication or dosage in past 3 months)
- Current or lifetime diagnosis of Bipolar Disorder
- Diagnosis of substance use disorder within past 12 months
- Diagnosis of psychotic-spectrum disorder such as Schizophrenia
- Pregnancy or probable pregnancy
- Medical illness or treatment that would prevent study participation
- Neurological disorder associated with brain damage
- History of seizures or head trauma with loss of consciousness longer than 5 minutes
- Family history of epilepsy or personal epilepsy/seizures
- Ferromagnetic implants or ferromagnetic objects within body (e.g., pacemaker)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Auburn University
Auburn, Alabama, United States, 36849
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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